What is tretinoin in skincare?
Tretinoin is all-trans retinoic acid – the biologically active form of vitamin A, and the only one that binds directly to retinoic acid receptors without needing conversion by the skin. It is available on prescription rather than over the counter.
It was the first topical treatment proven to reverse signs of photoageing, and remains the benchmark against which every other anti-ageing active is measured. Common strengths are 0.025%, 0.05% and 0.1%.
What skin concerns does tretinoin treat?
It treats acne at every severity by normalising how follicles shed, and it is extensively documented for photoageing – fine lines, wrinkles, roughness, sallowness and mottled pigmentation.
A vehicle-controlled comparison found 0.025% delivered improvement similar to 0.1% with markedly less irritation, so higher strength is not automatically better.
What ingredients are best paired with tretinoin?
Support the barrier hard: ceramides, hyaluronic acid, niacinamide, panthenol and squalane make the retinisation period far more tolerable. Applying moisturiser before tretinoin (the sandwich method) reduces irritation without eliminating benefit.
Use at night, start two or three times a week, and never skip morning SPF. Do not combine with AHAs, BHAs or benzoyl peroxide in the same application, and do not use it if you are pregnant or trying to conceive. Take our Skin Quiz.
What are sun spots?
Sun spots are flat patches of concentrated pigment that form where skin has taken the most ultraviolet exposure – cheeks, nose, forehead, hands, shoulders and chest. Dermatologists call them solar lentigines; they are the same thing as age spots.
They are harmless, but they are a visible marker of accumulated photodamage, and they usually arrive alongside other signs of it: fine lines, loss of firmness and an uneven overall tone.
What causes sun spots?
UV radiation prompts melanocytes to produce extra melanin as a defence. With repeated exposure that response becomes localised and fixed, leaving discrete patches instead of an even tan that fades.
Tanning beds, sunburns in childhood, fair skin and outdoor time without protection all increase the count. Incidental exposure – driving, walking, sitting near a window – adds up more than most people expect.
What ingredients are best for sun spots?
Retinoids to accelerate turnover, vitamin C to protect and brighten, and pigment inhibitors such as alpha arbutin, kojic acid, azelaic acid, tranexamic acid and liquorice root are the core toolkit.
Gentle AHAs help shift surface pigment, and niacinamide slows the transfer of melanin into skin cells. None of it holds without daily broad-spectrum SPF and reapplication. Take our Skin Quiz.