What is tretinoin in skincare?
Tretinoin is all-trans retinoic acid – the biologically active form of vitamin A, and the only one that binds directly to retinoic acid receptors without needing conversion by the skin. It is available on prescription rather than over the counter.
It was the first topical treatment proven to reverse signs of photoageing, and remains the benchmark against which every other anti-ageing active is measured. Common strengths are 0.025%, 0.05% and 0.1%.
What skin concerns does tretinoin treat?
It treats acne at every severity by normalising how follicles shed, and it is extensively documented for photoageing – fine lines, wrinkles, roughness, sallowness and mottled pigmentation.
A vehicle-controlled comparison found 0.025% delivered improvement similar to 0.1% with markedly less irritation, so higher strength is not automatically better.
What ingredients are best paired with tretinoin?
Support the barrier hard: ceramides, hyaluronic acid, niacinamide, panthenol and squalane make the retinisation period far more tolerable. Applying moisturiser before tretinoin (the sandwich method) reduces irritation without eliminating benefit.
Use at night, start two or three times a week, and never skip morning SPF. Do not combine with AHAs, BHAs or benzoyl peroxide in the same application, and do not use it if you are pregnant or trying to conceive. Take our Skin Quiz.
What is crepey skin?
Crepey skin is skin that has become thin, loose and finely wrinkled, with the papery texture of crepe paper. It differs from ordinary wrinkles in that it affects a broad area rather than forming distinct lines, and it appears most on the under-eyes, neck, décolletage, upper arms and inner thighs.
The hallmark is loss of elasticity: pinched skin takes longer to snap back, and the surface looks crinkled even at rest.
What causes crepey skin?
The main driver is degradation of the elastin network in the dermis. Cumulative ultraviolet exposure breaks down elastic fibres and replaces them with disorganised material – the process called solar elastosis – while collagen production falls at the same time.
Age, chronic dehydration, significant weight loss, smoking, and the natural drop in oestrogen around menopause all accelerate it. Body areas get less skincare attention than the face, which is why crepiness often shows there first.
What ingredients are best for crepey skin?
Retinoids remain the best-evidenced option for rebuilding collagen and thickening the dermis over months of use. Peptides support elastin and collagen signalling, and vitamin C protects existing fibres while aiding synthesis.
Layer those over rich hydration – hyaluronic acid, glycerin, ceramides, squalane and shea butter – which visibly improves the crinkled look even before structural change happens. Daily SPF on neck, chest and hands prevents further breakdown. Take our Skin Quiz.
