What is CoQ10 in skincare?
Coenzyme Q10, also called ubiquinone, is a fat-soluble compound found in the mitochondria of every cell. It has two jobs: it carries electrons in the process that generates cellular energy, and it acts as an antioxidant protecting cell membranes from oxidation.
Skin levels of CoQ10 fall steadily with age and are further depleted by UV exposure, which is the rationale for replacing it topically.
What skin concerns does CoQ10 treat?
It targets the energy side of skin ageing – tired, dull, thinning skin with reduced cell activity – alongside fine lines and loss of firmness.
Topical application has been shown to raise CoQ10 levels in the skin and increase its antioxidant capacity, and laboratory work links it to reduced UVB-induced wrinkle formation. It is well tolerated, including on sensitive skin.
What ingredients are best paired with CoQ10?
Stack it with other antioxidants for a wider defence: vitamin C, vitamin E, ferulic acid, resveratrol and green tea all cover different free-radical species.
It pairs safely with retinoids, peptides, niacinamide and hyaluronic acid, making it easy to slot into an existing anti-ageing routine. As with all antioxidants, it supports sunscreen rather than substituting for it. Take our Skin Quiz.
What is cystic acne?
Cystic acne is the most severe form of inflammatory acne. Instead of surface pimples, it produces deep, tender nodules and fluid-filled cysts that sit under the skin, often without ever coming to a head.
It happens when a blocked follicle ruptures deep in the dermis and spills sebum, keratin and bacteria into surrounding tissue, triggering a strong immune inflammatory response. Because the damage is deep, cystic acne is the type most likely to scar.
What causes cystic acne?
The same four factors behind all acne, amplified: excess sebum, abnormal shedding inside the follicle, overgrowth of Cutibacterium acnes, and inflammation. Androgens drive sebum production, which is why cystic acne often tracks with hormonal cycles, PCOS or puberty.
Genetics strongly influence severity, and stress, high-glycaemic diets, occlusive products and picking at lesions all make it worse. Squeezing a cyst pushes the contents deeper and reliably increases scarring.
What ingredients are best for cystic acne?
Cystic acne genuinely warrants a dermatologist – oral treatment is often needed. Alongside that, topical retinoids are the most useful over-the-counter active, because they work on the plug before it ruptures.
Benzoyl peroxide reduces bacterial load, azelaic acid calms inflammation and post-acne marks, and niacinamide helps redness without irritation. Keep the rest of the routine gentle and barrier-focused – harsh scrubs and drying alcohol make deep lesions angrier. Take our Skin Quiz.
