What is tretinoin in skincare?
Tretinoin is all-trans retinoic acid – the biologically active form of vitamin A, and the only one that binds directly to retinoic acid receptors without needing conversion by the skin. It is available on prescription rather than over the counter.
It was the first topical treatment proven to reverse signs of photoageing, and remains the benchmark against which every other anti-ageing active is measured. Common strengths are 0.025%, 0.05% and 0.1%.
What skin concerns does tretinoin treat?
It treats acne at every severity by normalising how follicles shed, and it is extensively documented for photoageing – fine lines, wrinkles, roughness, sallowness and mottled pigmentation.
A vehicle-controlled comparison found 0.025% delivered improvement similar to 0.1% with markedly less irritation, so higher strength is not automatically better.
What ingredients are best paired with tretinoin?
Support the barrier hard: ceramides, hyaluronic acid, niacinamide, panthenol and squalane make the retinisation period far more tolerable. Applying moisturiser before tretinoin (the sandwich method) reduces irritation without eliminating benefit.
Use at night, start two or three times a week, and never skip morning SPF. Do not combine with AHAs, BHAs or benzoyl peroxide in the same application, and do not use it if you are pregnant or trying to conceive. Take our Skin Quiz.
What is rosacea?
Rosacea is a chronic inflammatory skin condition that affects the central face – cheeks, nose, chin and forehead. It presents as persistent redness, visible broken capillaries, flushing that comes and goes, and in some subtypes acne-like papules and pustules.
Unlike acne, rosacea involves no comedones. It is driven by a combination of vascular hyper-reactivity, neurogenic inflammation and an overactive innate immune response, often with an impaired skin barrier alongside.
What causes rosacea?
There is no single cause. Genetic predisposition, an exaggerated immune response involving cathelicidin, overgrowth of Demodex mites, and dysfunction of the facial blood vessels all appear to contribute.
Flares are triggered by heat, sun exposure, alcohol, spicy food, hot drinks, exercise, stress, wind and cold, and by harsh skincare. Identifying and avoiding your own trigger set does as much as any product.
What ingredients are best for rosacea?
Azelaic acid and niacinamide are the standout actives – both reduce redness and inflammation without provoking the barrier. Sulphur, green tea extract, liquorice root and centella asiatica also calm reactive skin.
Build everything else around barrier repair: ceramides, glycerin, squalane and panthenol, with a gentle non-foaming cleanser and a mineral SPF every day. Avoid alcohol-heavy toners, fragrance, menthol, physical scrubs and high-strength acids. Take our Skin Quiz to build a routine your skin will tolerate.
